Diarrhea
Chronic diarrhea is an urgent matter.
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What Women Need To Know About Chronic Diarrhea
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Acute episodes of diarrhea, especially with bleeding, could be from a life-threatening disorder. If you are experiencing acute diarrhea with bleeding, seek care through the emergency department.
Overview
Chronic diarrhea is a persistent change in stool consistency, characterized by loose stools and increased frequency of more than three stools per day for at least four weeks. For women, chronic diarrhea is often linked to autoimmune disease, gut inflammation, bile acid malabsorption (BAM), and hormonal changes, making treatment a complex but necessary endeavor.
Traditional Gastroenterology Approaches to Chronic Diarrhea
Gastroenterologists typically diagnose chronic diarrhea by categorizing it into different types:
- Watery diarrhea – secretory vs. osmotic
- Fatty diarrhea – due to malabsorption
- Inflammatory diarrhea – often linked to conditions such as inflammatory bowel disease (IBD) or infections
Despite extensive testing, many cases of chronic diarrhea in women remain without a clear cause. External factors such as stress, hormonal fluctuations, and past medical exposures can all play a role. This highlights the importance of a patient-centered approach that considers diet, lifestyle, and mind-body therapies as potential interventions.
The Role of Autoimmune Diseases in Chronic Diarrhea
Approximately 80% of individuals diagnosed with autoimmune diseases are women.[8]Many autoimmune conditions, like celiac disease and inflammatory bowel disease, can impact gut health, leading to diarrhea. Celiac disease, an autoimmune disease and inflammatory bowel diseases, including Crohn’s disease, ulcerative colitis, and microscopic colitis, are more prevalent in women and can cause diarrhea. Despite traditional therapies many women continue to have symptoms and are never offered effective complementary treatments. For example, many women with chronic diarrhea may benefit from innovative therapies such as low-dose naltrexone (LDN), which has novel and paradoxical effects in autoimmune conditions. Yet, this treatment option is often overlooked in conventional practice.
Bile Acid Malabsorption: A Common but Underdiagnosed Cause
Bile acid malabsorption (BAM) is a significant but frequently undiagnosed cause of chronic diarrhea in women. Bile acids, produced by the liver and stored in the gallbladder, aid in fat digestion. When the regulation of bile acids is disrupted—due to gallbladder removal, medication use, or intestinal injury—excess bile acids accumulate in the colon, leading to diarrhea.
This condition is particularly relevant in women who have undergone cholecystectomy (gallbladder removal) or who suffer from irritable bowel syndrome (IBS), celiac disease, or Crohn’s disease. Studies suggest that altered bile acid metabolism in IBS can contribute to symptoms, making bile acid binders a potential therapeutic option.
Holistic and Medical Solutions for Chronic Diarrhea in Women
For many women, chronic diarrhea management requires a multifaceted approach, including:
- Dietary modifications – Identifying food triggers and incorporating gut-friendly foods
- Mind-body therapies – Stress reduction techniques such as yoga and meditation
- Probiotics and gut health supplements – Restoring microbiome balance
- Bile acid binders – Medications, like cholestyramine, that help regulate bile acid levels
- Targeted complementary therapies – Including low dose naltrexone (LDN)
Empowering Women with Effective Solutions
Women deserve tailored, effective treatments for chronic diarrhea that go beyond conventional medical approaches. By addressing gut inflammation, autoimmune conditions, and bile acid metabolism, GutsyRx provides women with evidence-based solutions that improve daily quality of life.
If you’re struggling with chronic diarrhea, GutsyRx is here to help with innovative, science-backed solutions designed specifically for women’s unique gut health needs!
Chronic Diarrhea Causes
This is a women-centric list of causes of chronic diarrhea. This list does not encompass all the causes of chronic diarrhea or represent the differential diagnosis of chronic diarrhea.
- Altered Gut Permeability
- Bile Acid Malabsorption (BAM)
- Celiac Disease
- Chronic Infections
- Chronic stress
- Crohns disease
- Dissacharidase deficiency
- Dysbiosis
- Endocrine Disorders
- Exocrine pancreatic insufficiency
- FODMAPs intolerances
- Food intolerance
- Hormone changes
- Inflammatory Bowel Disease
- Irritable Bowel Syndrome with Diarrhea (IBS-D)
- Medication Side Effects
- Microscopic Colitis
- Non-celiac gluten sensitivity
- Overflow diarrhea, meaning constipation
- Post antibiotic use
- Post-Cholecystectomy Syndrome
- SIBO (small intestinal bacterial overgrowth)
- Sugar alcohols (e.g., sorbitol)
- Ulcerative colitis
- Ulcerative proctitis
Signs and Symptoms
- Abdominal cramps
- Bloating
- Cramping or abdominal pain before stool
- Dehydration
- Diarrhea (frequent loose stools)
- Electrolyte imbalance
- Fatigue
- Fecal urgency (e.g, sudden and strong need to have a bowel movement)
- Feeling of urgency while exercising
- Frequent bathroom trips
- Loose runny stools
- Malabsorption
- Mucus in stool
- Post eating diarrhea
- Weight loss
GutsyRx Treatments For Chronic Diarrhea
GutsyRx provides treatments for chronic diarrhea that address symptoms with lifestyle guidance, integrative products, personalized oral medication. Depending on your preference and gut challenges, we’ll create a compounded prescription (Rx) just for you. Lifestyle guidance for chronic diarrhea relief during a consultation may include advice on stress reduction, avoiding triggers, hydration, vitamins, and/or supplements. The timeline for recovering from chronic diarrhea depends on the underlying diagnosis and response to treatment. All GutsyRx products are free of allergens, dyes, preservatives, and irritating FODMAPs.
8 Sources
GutsyRx is committed to providing high-quality, reliable information to support women facing gut and rectal health challenges. Our content is curated and reviewed by women doctors to ensure it is accurate, trustworthy, and relevant. We strive to be a dependable resource, empowering women with the knowledge they need for better gut and rectal health.
- Greuter, T., et al., Gender Differences in Inflammatory Bowel Disease. Digestion, 2020. 101 Suppl 1: p. 98-104.
- Singh, P., et al., Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol, 2018. 16(6): p. 823-836 e2.
- Camilleri, M., J.H. Sellin, and K.E. Barrett, Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea. Gastroenterology, 2017. 152(3): p. 515-532.e2.
- Koliada, A., et al., Sex differences in the phylum‐level human gut microbiota composition. BMC Microbiology, 2021. 21(1): p. 131.
- Dao, M.C., et al., <em>Akkermansia muciniphila</em> and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut, 2016. 65(3): p. 426-436.
- Zucker, I. and B.J. Prendergast, Sex differences in pharmacokinetics predict adverse drug reactions in women. Biol Sex Differ, 2020. 11(1): p. 32.
- Viswanathan, L. and S.S. Rao, Intestinal Disaccharidase Deficiency in Adults: Evaluation and Treatment. Curr Gastroenterol Rep, 2023. 25(6): p. 134-139.
- Angum, F., et al., The Prevalence of Autoimmune Disorders in Women: A Narrative Review. Cureus, 2020. 12(5): p. e8094.
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Meet Your Lady GI MD
Hi, I’m Dr. Emily Ward. I’m a board-certified gastroenterologist with 20+ years of professional experience and 30 + years of personal gut and rectal challenges. I am a mom of 2 kids with food allergies and a working mother navigating the everyday work-mom-life spectrum. With GutsyRx, I’m here to make sure you feel heard, seen, and cared for.
Meet Dr. Emily